This repository is the code for Tempera submitted to the M&Ms-2 challenge: https://www.ub.edu/mnms-2/. Details of the model can be found at: https://link.springer.com/chapter/10.1007/978-3-030-93722-5_29. The code is implemented in Python and all libraries and their versions can be found in the file 'environment.yml'.

The M&Ms-2 Challenge is a research project conducted by the University of Barcelona.

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Micro/nanomotors (MNMs) represent a kind of novel nanomaterial with autonomous movement and penetration capabilities, which provide an opportunity to overcome physiological barriers of TME. Due to the important role of MNMs in tumor therapy, the milestone of achievements involving MNMs is presented in Fig. 1 a.

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In the present study, we examined particle dispersion in an MNMs production facility during a hypothetical accidental release of TiO 2 MNMs. We identified some parts of the production machine where a malfunction could lead to the escape of the manufactured particles into the surrounding space.

Our finding that incorporating MNMs dramatically eliminates the signature of positive selection from many genes could have several causes, including: 1) the BS+MNM model may have reduced power to identify authentic positive selection compared to the BST, 2) it may ameliorate a false-positive bias in the BST caused by MNMs, or 3) the additional ...