Talzenna Plus Xtandi Shows Significant Overall Survival …
Oct 10, 2024 · The combination of Talzenna (talazoparib; Pfizer) plus Xtandi (enzalutamide; Astellas and Pfizer) produced a statistically significant improvement in overall survival (OS) in …
The CRA of the Future: From ‘Road Warrior’ to Site ‘Owner’
Feb 13, 2024 · The role of the clinical research associate (CRA) is fundamentally important to the success of clinical trials. However, this role is undergoing significant transformation due to the …
Tirzepatide Produces Clinically Meaningful Improvement in …
Jun 26, 2024 · Treatment with tirzepatide (Zepbound and Mounjaro; Eli Lilly) was found to improve sleep-related patient-reported outcomes, as well as apnea–hypopnea index (AHI) …
FDA Accepts Phase III RECOVER-2 Study for Brilaroxazine in …
Apr 16, 2024 · Reviva Pharmaceuticals has gained alignment from the FDA on its registrational Phase III program for brilaroxazine in schizophrenia. The FDA has also indicated that two …
Keytruda Significantly Improves Event-Free Survival in Phase III …
Oct 9, 2024 · Keytruda (pembrolizumab) produced a significant improvement in event-free survival (EFS) and major pathological response as a perioperative treatment for resected, …
Phase III Trials Show Long-Term Efficacy of Cobenfy Treating …
Nov 1, 2024 · Data from a pair of Phase III trials presented at the 2024 Psych Congress demonstrate that Cobenfy (xanomeline and trospium chloride) maintained long-term efficacy in …
Spotlight on Open-Label Extension Studies - Applied Clinical Trials
Jul 1, 2006 · Open-label extension (OLE) studies are common, but they do not receive as much attention as traditional Phase I through Phase IV studies. Enrollment into an OLE study …
Elrexfio Shows Deep and Durable Responses Extending Survival in ...
Jun 14, 2024 · Findings from the Phase II MagnetisMM-3 trial (NCT04649359) showed a significant survival benefit with Elrexfio (elranatamab-bcmm) in patients with heavily pretreated …
Creating Strategic Relationships: The Changing Face of Contract ...
Nov 6, 2023 · From the emergence of big data analytics to huge advances in precision therapies and trial technologies, the world of clinical research has transformed in recent years, leading to …
Consequences of Improper Data Collection
Oct 7, 2024 · In a recent video interview with Applied Clinical Trials, Erin Erginer, director of product, Certara discussed the growing complexity and volume of data in clinical trials.Data is …