An operational taxonomic unit (OTU) is an operational definition used to classify groups of closely related individuals.

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In microbial research, operational taxonomic units are used to analyse gene sequence data sets obtained through the use of modern sequencing technologies such as metagenomic sequencing and targeted next generation sequencing.

In 16S metagenomics approaches, OTUs are cluster of similar sequence variants of the 16S rDNA marker gene sequence. Each of these cluster is intended to represent a taxonomic unit of a bacteria species or genus depending on the sequence similarity threshold.

Operational Taxonomic Unit (OTU): a group of closely related individuals which are arranged together based on the similarity of specific sequences (usually the 16S rRNA gene). From: Computational and Structural Biotechnology Journal, 2021

Operational Taxonomic Unit (OTU) clustering is a fundamental concept frequently employed in microbiology research. To unravel the intricate details of species composition diversity within samples, it becomes imperative to cluster valid sequences.

An OTU is a cluster of organisms grouped together based on a set level of similarity, often using DNA sequences. OTUs serve as proxies for species or higher-level taxonomic groups when direct classification is impractical or when detailed taxonomic information is unavailable.

OTU (Operational Taxonomic Unit) は、近縁な個体をひとまとめに分類するための操作上の単位である。 この用語は、1963年にRobert R. SokalとPeter H. A. Sneathによって導入され、この時点ではOTUは単に研究の対象となる生物のグループを意味している [1]。 この意味で、OTUは生物を個体の類似性に基づいて分類する実用的な定義であり、古典的な リンネ式分類法 や現 …

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