Interleukin-1 beta (IL-1β) also known as leukocytic pyrogen, leukocytic endogenous mediator, mononuclear cell factor, lymphocyte activating factor and other names, is a cytokine protein that in humans is encoded by the IL1B gene.

Mar 30, 2025 · IL1B (Interleukin 1 Beta) is a Protein Coding gene. Diseases associated with IL1B include Gastric Cancer and Hereditary Diffuse Gastric Adenocarcinoma. Among its related pathways are MIF Mediated Glucocorticoid Regulation and Bacterial infections in CF airways.

Interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine that is crucial for host-defence responses to infection and injury [1]. It is also the best characterised and most studied of the 11 IL-1 family members.

Mar 26, 2025 · Interleukin-1beta moderates the relationships between middle frontal-mACC/insular connectivity and depressive symptoms in bipolar II depression. Intense impact of IL-1beta expressing inflammatory macrophages in acute aortic dissection.

IL-1–type cytokines are major mediators of innate immune reactions, and blockade of the founding members IL-1α or IL-1β by the interleukin-1 receptor antagonist (IL-1RA) has demonstrated a central role of IL-1 in a number of human autoinflammatory diseases.

Bead-Based Multiplex Immunoassay.

Nov 1, 2023 · We uncovered an inflammatory loop between tumour cells and interleukin-1β (IL-1β)-expressing TAMs, a subset of macrophages elicited by a local synergy between prostaglandin E 2 (PGE 2)...