Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of 'position', ensuring that the correct structures form in …

The Hox genes are a set of transcription factor genes that exhibit an unusual property: They provide a glimpse of one way in which gene expression is translated into the many different forms that...

Indeed, one of the most remarkable pieces of evidence for deep homologies among all the animals of the world is provided by the Hox genes. As mentioned in Chapter 11, not only are the Hox genes themselves homologous, but they are in …

Hox genes code for proteins that attach to molecular switches on DNA, turning other genes on and off. The DNA-binding piece of a Hox protein is called the homeodomain, and it's encoded by the homeobox.

Hox genes are members of the homeotic transcription factor family that play a key role in controlling the body plan along the cranio-caudal axis (also referred to as anterior–posterior), and specify segment identity of tissues within the embryo.

Nov 20, 2024 · We analyse HOX gene expression across cell types during development, finding that neural-crest derivatives unexpectedly retain the anatomical HOX code of their origin while also adopting the...

Hox genes encode evolutionarily conserved transcription factors that are essential for the proper development of bilaterian organisms. Hox genes are unique because they are spatially and temporally regulated during development in a manner that is ...

Dec 1, 2004 · In this review, the origin of the Hox and ParaHox gene clusters by duplication of a ProtoHox gene cluster, and the changes in their gene numbers in major Metazoan Transitions are reviewed...

In this commentary, we highlight recent reports that have provided novel insight into the origins of the mammalian Hox cluster, the role of Hox genes in the generation of a limbless body plan, and a novel putative mechanism in which Hox genes may encode specificity along the AP axis.

Feb 11, 2025 · Hox genes, a subset of homeotic genes, are integral to the genetic framework determining an organism’s body plan during embryonic development. Highly conserved across …