Figure 1: Endocrine cells in human pancreatic islets express cholinergic markers. Figure 2: Human alpha cells express vAChT and ChAT. Figure 3: Isolated human islets secrete acetylcholine (ACh) in ...

Alpha cells in the pancreas, which do not produce insulin, can convert into insulin-producing beta cells, advancing the prospect of regenerating beta cells as a cure for type 1 diabetes, according ...

In type 1 diabetes, these beta cells are destroyed by an autoimmune reaction, but also in type 2 diabetes their function is impaired. Regenerating functional beta cell mass has therefore become a ...

image: Immunofluorescence images of alpha cells highlighting induction of insulin protein upon loss of SMNDC1 view more . ... but also in type 2 diabetes their function is impaired.

The liver-function tests, bromsulfalein retention, alkaline phosphatase, cephalin flocculation, ... This shows an alpha cell (a) and its characteristic secretory granules (g).

If your beta cell function has been compromised or if you have conditions affecting your liver or kidneys, ... alpha cells store and release glucagon whereas beta cells produce and release insulin.

It’s always been accepted that beta cells don’t act alone, that they act together with other hormone-producing pancreatic cells – alpha, delta, and gamma cells – to maintain blood glucose ...

Lab-based models of human alpha cells are crucial for understanding alpha-cell (dys)function and blood sugar regulation. Recently, Quinn Peterson and colleagues from Mayo Clinic, ...