However, despite achieving engraftment levels of up to 70% in these models, problems such as breeding difficulties and inability to expand engrafted hepatocytes by serial transplantation have ...

On the contrary, there is minimal expression of class I HLA antigens on hepatocytes ... and chronic rejection occur after liver transplantation, but there is debate as to whether hyperacute ...

In summary, ES cells could be regarded as a prospective and unlimited source for hepatocyte transplantation and gene therapy. However, there is more than one hurdle that needs to be overcome ...

Liver cells, or hepatocytes, take on these many tasks ... of the most common causes of severe liver injury requiring liver transplantation in the U.S. Despite this, there is currently only one ...

Furthermore, there is a huge shortage of liver donors. A more recent approach is transplantation of mature liver cells, known as hepatocytes. “The problem is obtaining sufficient quantities of ...