Medscape6d
Gene Therapy for Inherited, Inflammatory and Infectious Diseases of the Lung
Gene therapy for CF and α1-ATD seeks to produce the missing or deficient gene product in vivo by transfecting pulmonary cells with a functional gene copy. Surfactant protein B (SP-B) deficiency ...
Medscape27d
Genetic Variability of Surfactant Protein-B and Respiratory Distress Syndrome: Clinical Implications
Genetic Variability of Surfactant Protein-B and Respiratory Distress Syndrome: Clinical Implications. MedGenMed 1(3), 1999 [formerly published in Medscape Pulmonary Medicine eJournal 3(2), 1999].
Pharmaceutical Technology19d
KL4 Surfactant by Windtree Therapeutics for Coronavirus Disease 2019 (COVID-19) Associated Acute Respiratory Distress Syndrome: Likelihood of Approval
The company benefits from the proprietary technology platform Aerosol Delivery System (ADS) with pulmonary surfactants or in combination with other products to treat pediatric and adult respiratory ...
BMJ19d
Why are preterm newborns at increased risk of infection?
also contributing to morbidity from pulmonary infections. Preterm infants exhibit reduced APPs in tracheal aspirates as compared with term infants. The surfactant proteins SP-A and SP-D produced by ...
Researchers find association between elevated levels of protein VEGF-B and impaired kidney function
In diabetic kidney disease, fat accumulates in the kidneys, leading to lipotoxicity and kidney damage. A recently published ...
The EMBO Journal3d
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
Disorders of surfactant protein biology cause dysfunction of alveolar type 2 cells and can lead to interstitial lung disease. This study describes the development of genetically manipulable, mature ...
Oil-based solution enables room temperature storage of protein therapeutics
A new storage technique can keep protein-based drugs and vaccines stable without keeping them cold. The discovery, led by researchers at Penn State, could eliminate the need for refrigeration for ...
Researchers discover how cigarette smoke impairs critical lung immune cells
Cigarette smoking is widespread and deadly, yet our understanding of how cigarette smoke actually causes serious respiratory ...
Science Daily6d
Lung Cancer News
Researchers Identify Key Mechanism in Human Lung Development Oct. 31, 2024 — Researchers have shown that the IGFBP3 protein plays a relevant role in human lung development. The results of the ...
Business Insider4d
Dietitians share 11 of the best high-protein foods for weight loss
Most nutrition experts recommend a protein-rich diet, so Business Insider asked dietitians to share their favorite high-protein foods for weight loss. Here's what they said. Peanut butter is full ...
Nature9d
Protein folding articles from across Nature Portfolio
Protein folding is the process by which proteins achieve their mature functional (native) tertiary structure, and often begins co-translationally. Protein folding requires chaperones and often ...