The intrinsic factor of cell senescence, PCBP2, was identified by unlabeled quantitative proteomics, and its biological role in in vitro replication senescence of human bone marrow mesenchymal stromal ...

MANILA, Philippines — Taipan Lucio Tan-led Philippine National Bank (PNB) recorded an 18-percent climb in its earnings last year to P21.2 billion on growth in its core businesses, particularly ...

Vaccines using messenger RNA, or mRNA, technology became widespread during the pandemic. With limited long-term studies available, the Trump administration is revisiting these vaccines. In response to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The adipokine apelin has been directly ...

Dr. Vinod Balachandran says mRNA vaccines could stimulate the immune system to recognize and attack pancreatic cancer cells. An experimental approach to treating pancreatic cancer with the messenger ...

Shares of biotechnology company Moderna (NASDAQ:MRNA) jumped 11.8% in the morning session after it continued to build on the 3% gain from Friday when it reported fourth-quarter 2024 financial results.

Summary: Scientists have developed a lipid nanoparticle system that enables mRNA to cross the blood-brain barrier, a long-standing challenge in neuroscience. In studies using mice and human brain ...

Researchers at the Icahn School of Medicine at Mount Sinai say they have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection ...

Protein changes in p21, p53, cyclin A1, cyclin A2, and cyclin E1 were consistent with the mRNA changes (P < 0.01). Additionally, the HIF-1α level of the HG + Rot group was significantly higher than ...

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the ...

Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the central nervous system. Nature Materials , 2025; DOI: 10.1038/s41563-024-02114-5 Cite This Page : ...