Nanoparticles of a certain size range, with minor macrophage uptake and prolonged blood half-life time can passively accumulate on tumors, taking advantage of the progressive permeation through ...

Lipid nanoparticles (LNPs) represent a highly promising nonviral delivery platform for a variety of therapeutic nucleic acids, including short interfering RNA (siRNA), mRNA (mRNA), single-guide RNA ...

Effect of nanoparticle shape on biodistribution & macrophage uptake The rate of internalization of a nonspherical nanoparticle depends on its angular orientation relative to the cell membrane.

Polymeric nanoparticles have been employed in a range of traditional ... Varying molecular weights of HA can target solid tumor-associated macrophages, allowing for easy combinations of different ...

A new wireless nanosystem uses light-activated nanoparticles to treat Parkinson’s by restoring damaged neurons and reducing harmful protein aggregates. Credit: SciTechDaily.com A novel wireless ...

We would like to share some important news with you. After years of bringing you the latest insights, analysis and innovation news from the pharma industries, we have made the difficult decision to ...

Attribution (BY): Credit must be given to the creator. Macrophages are the primary cells responsible for nanoparticle processing and mediating host immunological biological outcomes. Their cellular ...

Scientists engineered tiny vesicles to target cancer cells via DR5, showing strong tumor-killing effects in lab and animal studies. This therapy may offer an easily manufactured, off-the-shelf option ...

Nanotechnology, particularly the application of nanoparticles (NPs), represents an innovative approach to strengthen crop resilience and enhance the sustainability of agriculture. NPs have special ...