The LNP-mRNA modality is a novel approach that uses lipid nanoparticles to deliver messenger RNA into cells. The mRNA acts as ...

Effect of nanoparticle shape on biodistribution & macrophage uptake The rate of internalization of a nonspherical nanoparticle depends on its angular orientation relative to the cell membrane.

A new wireless nanosystem uses light-activated nanoparticles to treat Parkinson’s by restoring damaged neurons and reducing harmful protein aggregates. Credit: SciTechDaily.com A novel wireless ...

The French biotech company Nanobiotix announced today that it has dosed the first patient in the CONVERGE study, a Phase 2 randomized controlled clinical trial evaluating its potentially ...

Attribution (BY): Credit must be given to the creator. Macrophages are the primary cells responsible for nanoparticle processing and mediating host immunological biological outcomes. Their cellular ...

For example, neutrophils regulate ongoing inflammation by modulating macrophage function through efferocytosis ... To find out, we used nanoparticles composed of intracellular proteins (cell-derived ...

Scientists engineered tiny vesicles to target cancer cells via DR5, showing strong tumor-killing effects in lab and animal studies. This therapy may offer an easily manufactured, off-the-shelf option ...

This new nanoparticle offers a way to address the problem at its root by stabilizing and reducing the plaques. The research focuses on a type of immune cell called macrophages, which play a ...

More information: Junguang Wu et al, A nanoparticle-based wireless deep brain stimulation system that reverses Parkinson's disease, Science Advances (2025). DOI: 10.1126/sciadv.ado4927 ...

1Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University, Key Laboratory of Carcinogenesis and Cancer Invasion, Ministry of Education, Shanghai, P ...