The concept of using vaccines to treat cancers has been around for several decades. A vaccine was first approved for prostate cancer in 2010, and another was approved in 2015 for melanoma. Since then, ...

Wu and colleagues confirmed that cultured-microglia-carrying lipid droplets struggled with phagocytosis, poorly engulfing ...

The work will be of interest to cell biologists and biochemists working in metabolism ... by boosting M2 population which then synthesize and secrete catecholamines to promote thermogenesis. It is now ...

The evidence supporting the conclusions is convincing and the work will be of interest to cell biologists and biochemists working in metabolism ... augmentation of the alternatively activated M2 ...

M2-like tumor-associated macrophages (M2-like TAMs) are pivotal in OC progression and therapy. This study aims to establish a novel prognostic signature and identify M2-like TAM-related biomarkers in ...

These observations indicate that PPAR-γ may have an important role in macrophage differentiation as well as in macrophage lipid metabolism ... were washed in M2 medium (Specialty Media ...

Objective Sustained inflammation originating from macrophages is a driving force of fibrosis progression ... and serves as a connecting metabolic hub between endocannabinoid and lipid signalling ...

Lipid metabolism plays a crucial role in cellular energy metabolism and is closely associated with the occurrence and development of cancers. Recent research indicates that cancer lipid metabolism is ...

BPH macrophages do not distinctly categorize into M1 and M2 phenotypes. Instead ... Specifically, macrophage subpopulations with altered lipid metabolism pathways, demarcated by TREM2 and MARCO ...

The study, led by Prof. Charlotte Scott and her team, was published in Immunity and identifies a key role for lipid-associated macrophages (LAMs) and LAM-like Kupffer cells (KCs) in promoting recovery ...