In patients with DKA, the deficiency in insulin can be absolute, or it can be insufficient relative to an excess of counterregulatory hormones. In HHS, there is a residual amount of insulin ...

Key steps in this homeostatic response are the suppression of endogenous insulin secretion and a stimulus to the secretion of the counterregulatory hormones, glucagon and epinephrine, which act ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study.