With this model, researchers may be able to discover antibody drugs capable of targeting a wide range of infectious diseases.
Female sex is linked to a stronger association between sTREM2 and CSF p-tau in Alzheimer’s disease
This study examined whether sex, age, microglial activation or ApoE4 modulates the Aβ to p-tau axis, a critical event in the ...
Researchers have discovered that the protein Hmga1, found in zebrafish, can repair damaged mouse hearts by reactivating ...
A key pathological hallmark of Alzheimer’s are filamentous inclusions made of the microtubule associated protein ... Oxidized Tau fibrils were formed by combining 25 μM compact htau40 monomers with 50 ...
HH Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, U.K. HH Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol ...
This issue is especially significant in designing functional proteins, including enzymes and molecular binders ... approaches struggle with achieving the trade-off between sequence-structure ...
Summary: Researchers have uncovered how loss of the MeCP2 protein triggers early molecular changes leading to Rett syndrome, a severe neurological disorder. By studying adult mice, they demonstrated ...
Amyloid-β is a relatively small protein that forms toxic plaques in the brain contributing to the harmful effects of Alzheimer's disease. Another protein, hyperphosphorylated tau (pTau), also ...
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