acidocaldarius, which shows conserved amino acid motifs and apparent structural similarities with the eukaryotic Alg14/13 and bacterial MurG functional homologs. Activity assays along with HPLC, ...
However, natural Hsp104 variation remains largely unexplored. Here, we screened a cross-kingdom collection of Hsp104 homologs in yeast proteotoxicity models. Prokaryotic ClpG reduced TDP-43, FUS, and ...