TRIM32 impairs cellular insulin action by degrading cell surface insulin receptors in the liver ... we overexpressed TRIM32 in mouse primary hepatocytes. We found that ectopic expression of TRIM32 was ...
The discovery that RIPK1 deficiency sensitizes the liver to acute injury and hepatocyte apoptosis is based on convincing evidence, highlighting the importance of RIPK1 in maintaining liver homeostasis ...
To investigate the potential contribution of hepatocyte cellular senescence to the metabolic derangements associated with non-alcoholic steatohepatitis (NASH), we treated human hepatocyte cell lines ...