eLife21d
Proteome dynamics reveal Leiomodin 1 as a key regulator of myogenic differentiation
This valuable study offers insights into the role of Leiomodin-1 (LMOD1) in muscle stem cell biology, advancing our understanding of myogenic differentiation and indicating LMOD1 as a regulator of ...
Frontiers4mon
Research progress on S-palmitoylation modification mediated by the ZDHHC family in glioblastoma
zDHHC15 plays a role by palmitoylating the IL-6 receptor subunit gp130, inhibiting the IL-6/STAT3 signaling pathway. Through a positive feedback mechanism, zDHHC15 effectively suppresses GSCs’ sphere ...
Frontiers5y
Signaling Through gp130 Compromises Suppressive Function in Human FOXP3 + Regulatory T Cells
We show that high expression of the IL-6 family cytokine receptor subunit gp130 identifies Treg cells with reduced suppressive capacity ex vivo and in primary FOXP3 + clones. We further show that two ...
ahajournals.org6y
Understanding Angiotensin II Type 1 Receptor Signaling in Vascular Pathophysiology
Figure 1. Signal transduction mechanism of EGFR (epidermal growth factor receptor) transactivation by angiotensin II (AngII) in vascular smooth muscle cells leading to vascular remodeling. Please note ...