FOR centuries, gout has been a deeply misunderstood disease, associated only with jolly, indulgent, and often big men. When Henry VIII was diagnosed, it became firmly entrenched in popular belief ...

XORTX Therapeutics Inc. is a late-stage clinical pharmaceutical company focused on developing innovative therapies to treat progressive kidney disease. The company is actively involved in creating ...

XORTX Therapeutics (XRTX) announces the launch of a new late stage program to treat gout. The new drug development program – XRx-026 – will ...

XORTX to focus on late stage allopurinol intolerant gout program; discussion with FDA planned for first half 2025 regarding ...

This lets uric acid accumulate, crystallize, and settle in the joints. Managing gout is possible with medications, lifestyle changes, and a gout-friendly diet. This article reviews the best diets ...

Objective Macrophage activation by monosodium urate (MSU) and calcium pyrophosphate (CPP) crystals mediates an interleukin (IL)-1β-dependent inflammation during gout and pseudo-gout flare, ...

A recent survey reveals a significant decline in teen drug and alcohol use since 2017, reaching its lowest point in 2024. Researchers attribute this drop to pandemic lockdowns disrupting social ...

Lower back pain can affect one's ability to move comfortably and function throughout the day. Medications, including over-the-counter (OTC) and prescription drugs, are available to manage pain and ...

Colchicine, a medication commonly used for gout and other inflammatory conditions, has shown promise in managing inflammation. However, it is not currently approved for treating osteoarthritis ...

From 2017 to 2020, it increased to 41.9%. Prescription weight loss medication has become extremely popular because it is easy to take and effective. But, it is expensive, and people must also try ...

Experts debate the merits of using allopurinol as the first-line therapy for all gout patients versus tailoring treatment to the individual's hyperuricemia mechanism. A recent debate at the annual ...

Stamp emphasized the importance of drug availability and noted that allopurinol is also the only medication for gout that is on the World Health Organization list of essential medications.