In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known ...

MaizeCODE is a genomic project analyzing the genetic basis of maize domestication. Researchers identified key regulatory ...

Yale researchers have created "Ochre," a genomically recoded organism that enables the production of synthetic proteins with ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

In the case of MGX-001, it specifically guides the enzyme to make a cut in the gene encoding albumin, a blood protein that’s made in large quantities by the liver. The goal is to insert the healthy F8 ...

This happens through a process called epigenetics, whereby certain genes are expressed to a greater or lesser extent depending on a person’s surroundings. Abused children, for instance ...

It is caused by an inherited mutation in an allele of the HTT gene, in which a sequence of 3 DNA bases, C, A and G, is repeated at least 36 times. To understand why it takes so long for this ...