The SYNGAP1 gene, which supports the production of a protein called SynGAP (Synaptic Ras GTPase-Activating Protein), is known ...

in the generation of fusion genes encoding chimeric transcripts containing the first three exons of HMGA2 and ectopic sequences from other genes. HMGA protein overexpression is a constant feature ...

KIAA0368 is a gene that plays a role in how proteins are made or processed. SLC3A2 is a gene encoding a protein that transports things into and out of the cells. Neither of them has been ...

(2020) found FTase (farnesyltransferase)-dependent cellular factors (a cytokine that acts on RAS proteins) to be associated with ... TKOv1 library and discovered that mutations in three genes encoding ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

A new study has discovered in mouse models that genes associated with repairing mismatched DNA are critical in eliciting damages to neurons that are most vulnerable in Huntington's disease and ...

Dec. 10, 2024 — In a single IV injection, a gene therapy targeting cBIN1 can reverse the effects of heart failure and restore heart function in a large animal model. The therapy increases the ...

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Gene regulation refers to the mechanisms that act to induce or repress the expression of a gene. These include structural and chemical changes to the genetic material, binding of proteins to ...

Cardiff Oncology's Onvansertib shows promise in treating RAS-mutated cancers, especially mCRC. See why I rate CRDF stock as a ...

How is genetic information inherited? - OCR 21st Century Our genes are inherited from our parents, and the different combinations of these genes make us unique. Genetic inheritance controls the ...

This happens through a process called epigenetics, whereby certain genes are expressed to a greater or lesser extent depending on a person’s surroundings. Abused children, for instance ...