Rheumatologists report largely adhering to American College of Rheumatology guidelines for gout management, but show notable ...

Febuxostat 40 mg daily appears to be as efficacious as allopurinol in lowering serum uric acid levels. [38] Both febuxostat 40 and 80 mg can be given to patients with mild-to-moderate renal ...

and tolerability of serum uric acid lowering and maintenance with febuxostat in patients with gout. Febuxostat Open-label Clinical Trial of Urate-lowering Efficacy and Safety Adverse events were ...

The journey of Takeda’s gout med Uloric—which turned rocky in recent years—has come to an end in the U.S. | Following some ...

Gout affects around one in 40 people in ... Current first-line therapies like allopurinol and febuxostat can be very effective, but some patients – roughly 1% according to FDA estimates ...

current drugs like allopurinol and febuxostat aren’t able to achieve that objective, and there are estimated to be around 160,000 people facing with refractory gout in the US. If approved ...

Currently, we only compared the efficacy of benzbromarone administration, in the absence of a comparison with allopurinol or febuxostat. In summary, this study has demonstrated the positive effect of ...

Zyloprin (allopurinol), Uloric (febuxostat): These drugs are called xanthine oxidase ... This drug is reserved for people who have not had success with other gout medications. Hyperuricemia occurs ...

Eligible for inclusion were adult patients (≥18 years) with microscopically verified gout who initiated or increased ULT (allopurinol, benzbromarone or febuxostat). For the latter group, crystal ...

ULT was defined as one of the following medications, either alone or in combination: allopurinol, febuxostat, or probenecid (1). According to SUA levels, hyperuricemia was defined as SUA > 7.0 mg/dL ...