Centrosome abnormalities are hallmarks of various cancers and have been implicated in chromosome missegregation, chromosomal instability, and aneuploidy. Since genetic instability is a common ...

Researchers at the Francis Crick Institute have shown that the 'pacemaker' controlling yeast cell division lies inside the ...

Essentially, the centrosome in mammalian cardiac muscle cells undergoes a process of disassembly which is completed shortly after birth. “This disassembly process proceeds by some proteins ...

Many human tumours show centrosome aberrations, indicating an underlying deregulation of centrosome structure, duplication or segregation. Centrosomes organize microtubule arrays throughout the ...

"Centrosome amplification is found in human tumors but not in normal cells, so it is an appealing feature to explore for diagnosis, prognosis, and therapy," explains Carla Lopes, ...

Citation: Targeted centrosome inheritance during CD8⁺ T cell division plays role in memory precursor cell generation: Study (2025, January 9) retrieved 30 May 2025 from https://medicalxpress.com ...

Oncotarget: IQGAP1 control of centrosome function defines variants of breast cancer The cover for issue 26 of Oncotarget features Figure 6, 'Mislocalization of IQGAP1-BRCA1 in human TNBC tumors ...

Centrosome dysfunction contributes to diseases like cancer and congenital developmental disorders—for which understanding what regulates centrosome function is key.

All the latest science news on centrosome from Phys.org. Find the latest news, advancements, and breakthroughs.

The centrosome plays an important role in neuron migration. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2023 / 02 / 230215143329.htm ...

The article, "Centrosome Loss in the Evolution of Planarians," by Juliette Azimzadeh, Mei Lie Wong, Diane Miller Downhour, Alejandro Sánchez Alvarado and Wallace F. Marshall, is published in ...

Background: Centrosome amplification (CA) has been reported in all human cancers and is thought to result in aneuploidy and chromosomal instability (CIN). CA is associated with deleterious clinical ...