A genomic study of human and selected nonhuman primate centromeres has revealed their unimaginable diversity and speed of evolutionary change. In cell genetics, a centromere is the spot where two ...

Scientists have solved a decade-long question about the mechanism that preserves the centromere, the hub that ensures DNA ...

In the absence of DDM1 and RNAi, this TE doesn’t produce small RNAs, so the centromere is not methylated. These mutants also had few epigenetic tags on their histones, which contribute to the ...

With a few exceptions, eukaryotic chromosomes have a single centromere that ensures their accurate segregation during mitosis. Chromosomes that lack centromeres segregate randomly during mitosis ...

At the heart of the kinetochore is a specialized nucleosome that contains centromere protein (CENP)-A, a histone H3 homologue. Several inner kinetochore components (cyan and purple ovals ...

They found that two protein complexes work together to determine the centromere distribution during cell division: condesin II (CII) and the linker of nucleoskeleton and cotoskeleton (LINC). “The ...