Different cell types and signals combine to shape PC survival niches (5, 7). In humans, the phenotype of LLPCs is currently defined as CD19 neg CD138 + CD38 hi, but phenotypic, biological and ...
11,30 Cells were incubated with 2 µg/ml PE together with the respective surface makers for detection of PE-specific CD38 memory B cells. Anti-PE antibody producing plasma cells were identified by ...
CARsgen Therapeutics Holdings Limited, a company focused on innovative CAR T-cell therapies for the treatment of hematologic malignancies and solid tumours, announces that KJ-C2320, an allogeneic CAR ...
Share on Facebook. Opens in a new tab or window Share on Bluesky. Opens in a new tab or window Share on X. Opens in a new tab or window Share on LinkedIn. Opens in a new tab or window Daratumumab ...
Immunostaining for CD138 (Panel B) shows that plasma cells account for approximately 40% of the marrow cellularity. Hematoxylin and eosin staining of a section of the fat-pad biopsy specimen ...
The first patient with relapsed/refractory acute myeloid leukemia has received KJ-C2320, an allogeneic CAR T-cell therapy targeting CD38 and developed using the THANK-uCAR platform, in an investigator ...
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Normal University, Fuzhou, Fujian 350117 ...
The mucosal immune system is a critical first line of defense to infectious diseases, as many pathogens enter the body through mucosal surfaces, disrupting the balanced interactions between mucosal ...
Neoplastic cell morphology in peripheral blood (A) and bone marrow aspirate films (B) showing small- to medium-sized lymphoplasmacytic lymphocytes (May Grunwald Giemsa stain, 1000×). Bone marrow ...
ABSTRACT Introduction: The treatment of elderly multiple myeloma (MM) patients with autologous stem cell transplantation (ASCT) is a controversial procedure. Most clinical trials evaluating the safety ...
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