rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity. 21 cases were used in this study (age range 30-92). This immunostaining co-localized with ...

[Editors' note: this paper was reviewed by Review Commons.] We found that rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity. We further found that neurons ...

The contemporary clinical landscape of gastrointestinal stromal tumor (GIST) has evolved rapidly over the past several years. Widely used treatment guidelines – from the European Society of ...

Marianne J Middelveen; Cheryl Bandoski; Jennie Burke; Eva Sapi; Katherine R Filush; Yean Wang; Agustin Franco; Peter J Mayne; Raphael B Stricker Based on our experience with several hundred MD ...

“Efficacy compares favorably to historical data in previously treated GIST,” Jonathan C. Trent, MD, PhD, and study co-authors wrote in a poster presentation of the data. “Encouraging long-term safety ...

Bezuclastinib and Sutent combination therapy demonstrated improved PFS in GIST patients, especially those previously treated with Gleevec. The combination therapy targets multiple KIT mutations, ...

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late ...

Department of Chemistry and Chemical Biology, TU Dortmund University and Drug Discovery Hub Dortmund (DDHD), Zentrum für Integrierte Wirkstoffforschung (ZIW), Otto-Hahn-Strasse 4a, Dortmund 44227, ...

Cheryl Gist Penn passed away in her home in Austin, Texas on the morning of Saturday, January 18th, at the young age of 65. Although she left us far too soon, she made the most of every single day ...