Bezuclastinib and Sutent combination therapy demonstrated improved PFS in GIST patients, especially those previously treated with Gleevec. The combination therapy targets multiple KIT mutations, ...

Gastrointestinal bleeding in GIST patients significantly impacts recurrence-free and overall survival, with gastric bleeding linked to worse prognosis. Bleeding is less common in the small intestine, ...

Cheryl Gist Penn passed away in her home in Austin, Texas on the morning of Saturday, January 18th, at the young age of 65. Although she left us far too soon, she made the most of every single day ...

Gift Article 10 Remaining As a subscriber, you have 10 articles to gift each month. Gifting allows recipients to access the article for free. Crain’s residential real estate reporter Dennis ...

The tool outperformed PD-L1 immunostaining in predicting outcomes from ICI treatment. “Our long-term goal is to democratize precision oncology,” Diego Chowell, PhD, assistant professor at ...

Despite significant therapeutic advances, breast cancer remains a leading cause of cancer-related death in women. Treatment typically involves surgery and follow-up hormone therapy, but late ...

The contemporary clinical landscape of gastrointestinal stromal tumor (GIST) has evolved rapidly over the past several years. Widely used treatment guidelines – from the European Society of ...

The authors initially determined gene expression levels within the different lobes and regions of the mouse prostate, focusing on candidate stem cell markers -- in particular CD117 (also known as ...

“Efficacy compares favorably to historical data in previously treated GIST,” Jonathan C. Trent, MD, PhD, and study co-authors wrote in a poster presentation of the data. “Encouraging long-term safety ...

rG4 immunostaining strongly increased in the hippocampus with both age and with AD severity. 21 cases were used in this study (age range 30-92). This immunostaining co-localized with ...