Scale bar: 1mm. In this study, we provide genetic and pharmacological evidence to implicate the β1 adrenergic receptor (β1AR) in the pathogenesis of CCM. Our data suggest that inactivating β1AR via ...

Last year, the phase II SYCAMORE study evaluating two doses of REC-994 in CCM patients met its primary safety endpoint. Based on the success of the mid-stage study, Recursion plans to meet with ...

Shock is a severe, life-threatening medical condition with a high mortality rate worldwide. All four major categories of shock (along with their various subtypes)—hypovolemic, distributive, ...

Mitochondria are essential organelles for cell metabolism, growth, and function. Mitochondria in lung cells have important roles in regulating surfactant production, mucociliary function, mucus ...

20 µg PCR product was immobilized to 5 µl Streptavidin Sepharose High Performance Bead (GE Healthcare, Piscataway, NJ, USA), and then annealed to 1 µl sequencing primer (5 μM) for 2 min at 80°C.