eLife12d
Transcriptional Dynamics Uncover the Role of BNIP3 in Mitophagy during Muscle Remodeling in Drosophila
This paper presents the important finding that BNIP3/NIX, a mitophagy receptor, and its binding to ATG18 are required for mitophagy during muscle cell reorganization in Drosophila. Although the ...
Frontiers2mon
αAsarone alleviates neuronal injury by facilitating autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway in ischemia stroke
and enhanced neuronal autophagy via miR-499-5p/PDCD4/ATG5 signaling pathway. Discussion: Our data suggest that αAsarone alleviates neuronal injury of stroke by facilitating neuronal autophagy through ...
Frontiers3y
Therapeutic Targeting of Autophagy in Pancreatic Ductal Adenocarcinoma
2010). Hypoxia has been shown to increase transcription of the essential autophagy genes MAP1LC3B and ATG5 via the transcription factors ATF4 and CHOP, respectively. Notably, MAP1LC3B and ATG5 are not ...
eLife5y
Dynamic post-translational modification profiling of Mycobacterium tuberculosis-infected primary macrophages
Most of these cellular changes were not captured by mRNA profiling, and included activation of ubiquitin-mediated autophagy, an evolutionarily ancient cellular antimicrobial system. This analysis also ...