All lanes of the southbound 405 Freeway in Encino have reopened after an hours-long closure for a deadly crash.

A deadly crash involving a wrong-way driver forced the closure of the southbound 405 Freeway through the Sherman Oaks area ...

One person is dead and two others were injured following what investigators believe was a wrong-way crash involving three ...

The Department of Homeland Security has cut 405 employees from its workforce, a DHS official first told ABC News on Friday.

At least one person was killed in a reported wrong-way crash on the 405 Freeway in Encino that temporarily shut down of all ...

PORTLAND, Ore. (KPTV) - Northbound Interstate 405 is closed early Wednesday morning due to a rollover crash involving a ...

LOS ANGELES - A woman and a dog were killed in a crash on the 405 Freeway on Friday night, and three other people were ...

Two separate crashes involving big rigs on the 5 and 405 Freeways made for a tough commute on what was a foggy morning in Los Angeles.

A woman and a dog were killed in a crash on the 405 in Westwood. Three other people were also injured, and another dog ...

California Highway Patrol officers responded at 4:06 a.m. to the southbound 405 near the Valley Vista Boulevard exit.