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The authors present a histologic and immunohistochemical study of a case of primary thymic adenocarcinoma, an exceedingly rare cancer for which there is little genetic data.

Also, in the involuted thymus, glandular or tubular structures can be found. [7] Therefore, adenocarcinomas can result from extreme glandular differentiation during tumor progression.

Thymoma screening is recommended at the onset of myasthenia gravis (MG) or when patients with MG present with clinical deterioration or a progressive increase of anti-acetylcholine receptor antibody.