According to a case–control study published in Neurology, the expression of proinflammatory cytokines is elevated in the affected skin of patients with small-fiber neuropathy (SFN).

Nerve biopsy findings in length-dependent diabetic ... (A) This patient had a severe small-fiber sensory and autonomic polyneuropathy. (B) This patient had a severe length-dependent sensory ...

“We could already quantify small sensory fibers using intra-epidermal nerve fiber density (IENFD ... staining or preparation of the skin biopsy is required, allowing the SGNFD technique to ...