Frontiers19d
Bioinformatical analysis and experimental validation of endoplasmic reticulum stress-related biomarker genes in type 2 diabetes mellitus
After the intersection, 973 ERS-related protein genes were obtained and used for the subsequent analysis. GO and KEGG pathway enrichment analysis ... The GO settings include molecular function (MF), ...
C&EN22d
Membrane Interactions of GET1 and GET2 Facilitate Fiber Cell Initiation through the Guided Entry of the TA Protein Pathway in Cotton
National Nanfan Research Institute (Sanya), Chinese Academy of Agricultural Sciences, Sanya 572024, Hainan, China ...
ScienceAlert27d
This Mysterious Molecule Is Crucial to Brain Health, And We May Finally Know Why
The more we can understand the biological pathways responsible for cognitive decline, the closer we can get to better managing these cureless conditions. Much like our hands, molecules can have right ...
eLife27d
LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling
This study provides useful evidence substantiating a role for long noncoding RNAs in liver metabolism and organismal physiology. Using murine knockout and knock-in models, the authors invoke a ...
C&EN28d
Targeted Degradation of Receptor-Interacting Protein Kinase 1 to Modulate the Necroptosis Pathway
Get article recommendations from ACS based on references in your Mendeley library. Pair your accounts. Export articles to Mendeley Get article recommendations from ACS based on references in your ...
C&EN1mon
Scientists reject a binary view of human sex at NIH symposium
SRY influences the expression of several transcription factors and genes along a biological pathway heavily involved in sexual development. Variations can happen at each step in the pathway ...
Frontiers1mon
Monocrotaline-mediated autophagy via inhibiting PI3K/AKT/mTOR pathway induces apoptosis in rat hepatocytes
In summary, this study demonstrates that MCT-induced autophagy via inhibition of the PI3K/AKT/mTOR pathway can lead to apoptosis in PRHs. Hepatocytes underwent lysis ... 10 min to isolate the ...
Medscape1mon
The Intestinal Absorption of Biliary and Dietary Cholesterol as a Drug Target for Lowering the Plasma Cholesterol Level
The level of LDLR activity in the hepatocyte shifts in accordance ... which is governed by the balance between the various pathways that dictate the synthesis, storage, and excretion of ...