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Phosphatidic Acid Is a pH Biosensor That Links Membrane Biogenesis to Metabolism. Science , 27 August 2010: 1085-1088 DOI: 10.1126/science.1191026 Cite This Page : ...

Phosphatidic acid is important for the formation of double membrane vesicles, serving as replication organelles of hepatitis C virus and SARS-CoV-2, and offering a possible host targeting strategy ...

The lipid composition of the mitochondrial membrane, in particular, synthesis of phosphatidic acid, regulates mitochondrial size by modulating fusion and fission cycles.

Hepatic Gluconeogenesis Is Enhanced by Phosphatidic Acid Which Remains Uninhibited by Insulin in Lipodystrophic Agpat2-/- Mice. Journal of Biological Chemistry , 2014; 289 (8): 4762 DOI: 10.1074 ...

Activation of the transcription factor SREBP-1c stimulates the synthesis of lipogenic enzymes such as acetyl-CoA carboxylase-1 (ACC1) and fatty-acid synthase (FAS). [ 100 ] ...

Having previously demonstrated that endogenous phosphatidic acid (PA) promotes liver regeneration after acetaminophen (APAP) hepatotoxicity, the authors of this paper hypothesize that exogenous PA ...