In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

An improved understanding of the mechanisms driving vascular smooth muscle cell (VSMC) modulation in the diseased vessel wall is needed to improve our approach to atherosclerotic plaque cap ...

Myocardial remodeling is a key pathophysiological basis of heart failure, which seriously threatens human health and causes a severe economic burden worldwide. During chronic stress, the heart ...

Primary aldosteronism (PA) is the most common type of endocrine hypertension, and numerous experimental and clinical evidence have verified that prolonged exposure to excess aldosterone is responsible ...

#SBATCH --time=02:00:00 # max time before job cancels #SBATCH --mem=64GB # memory #SBATCH --cpus-per-task=8 #SBATCH --array=0-83 # Create directory and set variables ...

This repo contains the code use to analyze and visualize the data collected from MPRAs performed on VSMCs for BioRxiv 10.1101/2024.10.07.617126 As a brief summary: massively parallel reporter assays ...

Department of Drug Chemistry and Technologies, Sapienza University of Rome, P.le Aldo Moro 5, Rome 00185, Italy ...