In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Additional AEs observed more frequently in MS and in renal transplant clinical trials with FTY720 were respiratory disorders, mainly dyspnea. [10, 12, 144] During the core study of the Phase II ...

Growth factors secreted from VSMC play an important role in mediating various cellular responses in the development of cardiovascular diseases. 9 – 11 Recent evidence suggests that many other stimuli ...

Despite these inconsistencies, few alternative structural and cellular mechanisms have been considered. Bézie and colleagues have previously speculated that the connections between vascular smooth ...

Air Liquide will build, own and operate, through a significant investment of ~€70 MM, a new industrial gas production facility in Singapore. In the framework of the long-term agreement, large volumes ...

Sesamin significantly inhibited platelet-derived growth factor (PDGF)-induced VSMC proliferation (inhibition percentage at 1, 5, and 10 μM sesamin was 49.8 ± 22.0%, 74.6 ± 19.9%, and 87.8 ± 13.0%, ...

In VSMC transdifferentiation, there is an increase in the release of matrix vesicles, which resemble those released by osteoblasts (Kapustin et al., 2015). Matrix vesicles are a form of extracellular ...

3.3 PDGF/PDGFR pathway-driven stromal remodeling PDGF ligands and their receptors, PDGFRα and PDGFRβ, play pivotal roles in regulating biological functions such as cell growth, survival, and migration ...

Background: Recently, it was suggested that arginase (ARG)1 plays an important role in atherogenesis. However, because of its complex functions depending on vascular cell type, its impact on ...