Macrophage and Mast-Cell Invasion of Tumor Cell Islets Confers a Marked Survival Advantage in Non–Small-Cell Lung Cancer. JCO 23 , 8959-8967 (2005). DOI: 10.1200/JCO.2005.01.4910 ...

Mast cells are long-lived cells that, similar to monocytes and macrophages, can re-enter the cell cycle and proliferate following appropriate stimulation.

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

More information: Kenji Oishi et al, MHC Class II‐Expressing Mucosal Mast Cells Promote Intestinal Mast Cell Hyperplasia in a ...

The publication titled “Regulation of Mast Cells by Overlapping but Distinct Protein Interactions of Siglec-6 and Siglec-8” details efforts to ... in the presence of activated macrophages.

Macrophages upregulate mural cell-like markers and support healing of ischemic injury by adopting functions important for vascular support. Nature Cardiovascular Research, ...

Mast cells also play a role in pathogen recognition and elimination. In the context of bacterial infections, this function is primarily associated with the expression of toll like receptors (TLR’s) ...

Resolution Therapeutics has raised £63.5m ($83.3m) in a Series B financing round to develop its macrophage cell therapies. The UK-based company plans to use the money to finance the Phase I/II ...

Mast cell activation syndrome (MCAS) is a condition that occurs when the mast cells in your body release too much of a substance that causes allergy-like symptoms, according to Healthline.

Q: My doctor thinks my mast cells are activating inappropriately and may be causing many of the symptoms I periodically have. Please tell me more about this condition. A: Mast cells are an ...

An NHS GP has warned that millions of people in the UK could be unknowingly suffering a little-known condition that puts them at risk of a deadly allergic reaction. Mast cell activation syndrome ...