G protein-coupled receptors (GPCRs) play a crucial role in cellular communication and are involved in various physiological processes. One of their significant functions is the regulation of ...

Plants deploy cell-surface and intracellular immune receptors to recognize pathogens. In a comparative analysis of 808 angiosperm genomes, we reveal that during plant adaptation to diverse special ...

Lung metastases are a devastating reality for over half of cancer patients whose tumors spread beyond their initial sites.

Enhances B Cell Responses in Type 2 Inflammation Through IL-17RB Receptor,” published in the January 2025 issue of Allergy ...

This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Discover the potential of macrocycles in drug discovery: flexible, cell-permeable molecules targeting undruggable proteins.

Here, we use a synthetic amphiphile to modulate the membrane mechanical properties of cell-derived vesicles and probe channel activation. Using precise membrane mechanical characterization approaches ...

Kennedy once again betrays his ignorance about Medicaid. “The premiums are too high, the deductibles are too high, and everybody’s getting sicker,” he said. But Medicaid has no premiums or ...

Our mission is to provide a state-of-the-art facility, expertise, and education in advanced quantitative light microscopy to support Drexel University’s research community The Cell Imaging Center (CIC ...

Patrick Holland has been a phone reviewer for CNET since 2016. He is a former theater director who occasionally makes short films. Patrick has an eye for photography and a passion for everything ...

Innate lymphoid cells (ILCs) resemble lymphocytes, but lack the key characteristics of adaptive immune cells, namely an antigen-specific receptor. ILCs interact closely with IECs and fulfil an ...

1 Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, the Netherlands 2 Department of Experimental Internal Medicine, Academic Medical Centre, Amsterdam, the Netherlands ...