With this model, researchers may be able to discover antibody drugs capable of targeting a wide range of infectious diseases.

Researchers have discovered that the protein Hmga1, found in zebrafish, can repair damaged mouse hearts by reactivating ...

A key pathological hallmark of Alzheimer’s are filamentous inclusions made of the microtubule associated protein ... Oxidized Tau fibrils were formed by combining 25 μM compact htau40 monomers with 50 ...

HH Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol BS8 1TL, U.K. HH Wills Physics Laboratory, University of Bristol, Tyndall Avenue, Bristol ...

This issue is especially significant in designing functional proteins, including enzymes and molecular binders ... approaches struggle with achieving the trade-off between sequence-structure ...

Summary: Researchers have uncovered how loss of the MeCP2 protein triggers early molecular changes leading to Rett syndrome, a severe neurological disorder. By studying adult mice, they demonstrated ...

including physical protein-protein interactions, regulatory relationships, signaling and metabolic pathways, and functional associations, each of which contribute to our understanding of molecular and ...

Amyloid-β is a relatively small protein that forms toxic plaques in the brain contributing to the harmful effects of Alzheimer's disease. Another protein, hyperphosphorylated tau (pTau), also ...

MOST of the determinations of molecular weights of the proteins carried out in this laboratory by means of the ultracentrifugal method were made on material which had been subject to purification ...

molecular glues and PROTACs. Our results demonstrate that SIMPL2 is a sensitive, cost- and labor-effective tool suitable for high-throughput screening (HTS) in both PPI mapping and drug discovery ...

The image is miscaptioned. It's from 2021 and shows a fire at a chemical plant in Illinois that had no reported fatalities. There is no evidence of a bus crash in December 2024 that killed 135 or ...