This stark possibility has been studied by scientists, and findings have been published in the journal ACS Chemical ... are tau proteins Tau proteins are essential for maintaining the structure ...
HSV-1 is a common virus. During infection, its DNA incorporates into host chromosomes, where it lies dormant. An estimated two-thirds of adults worldwide carry these latent HSV-1 genes. Previous work ...
An international conference focusing on the Hsp90 molecular chaperone was ... had been suggested to form stable client protein complexes, this twisted structure instead prompts speculation on ...
This study showed, using a variety of techniques, that HSV-1 proteins are indeed present in brain samples from Alzheimer's patients and in organoid models of the disease. Aberrant tau proteins, which ...
Their new research has also revealed how tau protein may initially protect the brain from the virus but later contributes to brain damage. The findings are published in Cell Reports in an article ...
Scientists have visualized the detailed structure of protein clumps linked to Huntington's disease, offering critical ...
Amyloid-β is a relatively small protein that forms toxic plaques in the brain contributing to the harmful effects of Alzheimer's disease. Another protein, hyperphosphorylated tau (pTau), also ...
This study examined whether sex, age, microglial activation or ApoE4 modulates the Aβ to p-tau axis, a critical event in the ...
Conventional small-molecule drugs for reducing pTau include phosphatase activators of PP2A, and kinase inhibitors of GSK3β, CDK5, etc., as well as active or passive immunotherapies targeting pTau.