The hypothalamus consists of several nuclei that integrate peripheral signals, such as adiposity and caloric intake, to regulate important pathways within the CNS controlling food intake.

A comprehensive atlas of the human hypothalamus, a brain region that regulates many bodily functions, including temperature, sleep and appetite, has been built using single-cell RNA sequencing and ...

"In particular, the question of whether hypothalamus nuclei contribute to the stimulating ... hypothalamic activity, and ...

Researchers at Brown University and Cincinnati Children’s found that suppressing opsin 3 in the brain of mice makes them eat ...

A high-resolution spatial map of the human hypothalamus makes it possible to identify specific cells, determine their exact ...

The hypothalamus is a central region of the brain that controls vital functions such as sleep, body temperature, hunger and thirst. Because the human brain is difficult to study, much knowledge about ...

For this purpose, we aimed to investigate whether CLK2 is expressed in the hypothalamic nuclei and whether hypothalamic CLK2 is part of insulin and leptin signaling and action. We also aimed to ...

This important study assessed the effects of food intake on sharp wave-ripples in the hippocampus of mice during subsequent sleep. Solid evidence supports the conclusion that sharp wave-ripples are ...

There are projections from the ARC to other hypothalamic nuclei, as well as the cerebral cortex and reward pathways. Multiple neuropeptides have been identified that appear to modulate pathways ...