Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...
Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...
Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or ...
The Rice lab of bioengineer Gang Bao and collaborators at Baylor College of Medicine have developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the ...
Polyploidy, the existence of cells containing more than one pair of chromosomes, is a well-known feature of mammalian hepatocytes. Polyploid hepatocytes are found either as cells with a single ...
This study presents an investigation into the physiological functions of RIPK1 within the context of liver physiology, particularly during short-term fasting. Through the use of hepatocyte-specific ...
This important study provides insights into the physiological role of RIPK1 in liver physiology, particularly during short-term fasting. The discovery that RIPK1 deficiency sensitizes the liver to ...
Approximately 95% of the creatine pool in the body is found in skeletal muscle, while 5% is found in other tissues with high energy demands such as cardiomyocytes, hepatocytes, kidney cells, inner ear ...
Beale, “Biosynthesis of the Tetrapyrrole Pigment Precursor, d-Aminolevulinic Acid, from Glutamate,” Plant Physiology, Vol ... of Uroporphyrinogen Synthase on Porphyrin Metabolism in Hepatocyte Culture ...
Validation studies were conducted in primary mouse hepatocytes treated with ALA and DFO and in two mouse models of EPP- the Ferrochelatase mutant 1 with a pedigree from Pas (Fechm1Pas) mice and ...