The preclinical evaluation of drug-induced cardiotoxicity is an important stage in the drug development process; however, traditional methods for screening drug candidates, such as cardiomyocyte-based ...

While the common ancestor of vertebrates with synovial joints is still a mystery, the oldest specimen with evidence of these ...

Ten years ago, nobody knew that Asgard archaea even existed. In 2015, however, researchers examining deep-sea sediments ...

In the rapidly evolving field of drug discovery, single-cell analysis has become an invaluable tool for understanding cellular heterogeneity and molecular | Drug Discovery And Development ...

Microglia are brain-resident macrophages playing pivotal roles in CNS development and homeostasis. Yet, the cellular and molecular basis governing microglia maintenance ...

For decades, scientists were baffled by why thorny skates in the North Atlantic came in two distinct sizes. Despite extensive ...

CURE provides access to the cancer news, latest oncology research & expert insights that serve as a guide to every stage of the cancer experience.

High-throughput screening methods provide efficient measurement of the effects of agents or conditions in biological or chemical assays. These methods often require robotics, imaging and ...

The French director Alain Guiraudie’s latest film, a bent kind of murder mystery, presents life at its basest and gamiest. By Wesley Morris This gimmicky thriller starring Bill Skarsgard and ...

2004. Evolutionary origins of lymphocytes: Ensembles of T-cell and B-cell transcriptional regulators in a cartilaginous fish. J Immunol 172:5851-5860. Miracle AL, MK Anderson, RT Litman, CJ Walsh, CA ...