Rheumatologists report largely adhering to American College of Rheumatology guidelines for gout management, but show notable ...

and tolerability of serum uric acid lowering and maintenance with febuxostat in patients with gout. Febuxostat Open-label Clinical Trial of Urate-lowering Efficacy and Safety Adverse events were ...

An alternative XOI, Febuxostat, launched in the US in 2009 with the ... our XRx-026 program for the treatment of allopurinol intolerant gout; and 3) our secondary program in XRx-101 for acute kidney ...

Febuxostat 40 mg daily appears to be as efficacious as allopurinol in lowering serum uric acid levels. [38] Both febuxostat 40 and 80 mg can be given to patients with mild-to-moderate renal ...

The journey of Takeda’s gout med Uloric—which turned rocky in recent years—has come to an end in the U.S. | Following some ...

An alternative XOI, Febuxostat, launched in the US in ... our XRx-026 program for the treatment of allopurinol intolerant gout; and 3) our secondary program in XRx-101 for acute kidney and other ...

Your doctor may also suggest a medicine to lower your uric acid, which can build up to cause gout attacks. Allopurinol (Lopurin, Zyloprim) Febuxostat (Uloric) Probenecid (Probalan) Pegloticase ...

Gout affects around one in 40 people in ... Current first-line therapies like allopurinol and febuxostat can be very effective, but some patients – roughly 1% according to FDA estimates ...

current drugs like allopurinol and febuxostat aren’t able to achieve that objective, and there are estimated to be around 160,000 people facing with refractory gout in the US. If approved ...

Medications commonly used to treat gout include nonsteroidal anti-inflammatory drugs (NSAIDs), colchicine, corticosteroids, and xanthine oxidase inhibitors (e.g., allopurinol, febuxostat ...