Study uses clues from body to understand signaling in brain
The first clue about the possible connection between brain and muscle cells came when Janelia scientists noticed something ...
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E64FC26 inhibits inflammation and joint destruction in rheumatoid arthritis models
Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the endoplasmic reticulum.
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Endoplasmic Reticulum Stress, Inflammation, and Perinatal Brain Damage
The ER is an intracellular organelle consisting of a membranous network that extends throughout the cytoplasm of the cell and is contiguous with the nuclear envelope. In eukaryotic cells, the ER ...
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High-resolution imaging reveals ladder-like structure of the endoplasmic reticulum in neurons (VIDEO)
New research details the subcellular structures in neurons that enable signals to be transmitted from where they are received at specific sites on dendrites to the decision-making cell body located ...
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Protein Inhibitor Eases Cartilage Damage in Arthritis Model
Protein disulfide isomerases (PDIs) are essential enzymes that facilitate the proper folding of proteins and maintain protein quality within the ...
InFlectis BioScience Announces Promising Results for IFB-088 in a Phase 2a Clinical Study in Bulbar-Onset ALS Patients
InFlectis BioScience SAS, a drug discovery company pioneering development of therapeutics harnessing the Integrated Stress ...