A novel strategy using lipid nanoparticles to reprogram liver immunity shows promise in generating antitumor responses ...

Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Macrophages are important components of the internal immune cells, which profoundly affects the internal ...

European Commission approves Bristol Myers Squibb’s Opdivo plus Yervoy for first-line treatment of adult patients with unresectable or advanced HCC: Princeton, New Jersey Monday ...

[100] Once the Th2 polarization process is complete, IL-4 and IL-13 promote binding of costimulatory molecules (CD40 with CD40 ligands and CD80 or CD86 with CD28) on Th2 cells and B cells ...

Vitamin C Up-regulates Expression of CD80, CD86 and MHC Class II on Dendritic Cell Line, DC-1 Via the Activation of p38 MAPK. Dendritic Cell (DC) Vaccine in Mouse Lung Cancer Minimal Residual ...

All DCs express the surface markers CD11c, CD45, MHC II and CD135. The cDC2 subset is CD4 + and expresses CD11b, CD80, CD86 and CD40 but do not express CD8 and CD205 otherwise expressed by cDC1.

IL-27 promotes the production of inflammatory cytokines such as TNFα, IL-6, and IP-10 and surface markers such as HLA-DRA, CD80, and CD86 in monocytes after caspse-1, LPS, IFNγ, TLR7, and TLR8 ...

Humans have been attempting to combat cancer since the time of the Ancient Egyptians, and recent decades have seen remarkable progress. However, tumor cells have developed sophisticated ways to evade ...

2 Biomedical Institute for Pioneering Investigation via Convergence and Ministry of Education Key Laboratory of Cell Proliferation and Differentiation, Beijing, China 3 Beijing Advanced Innovation ...