In response to pathogens, vaccines, and other antigenic stimuli, BCR and TCR repertoires undergo changes through clonal expansion, somatic mutation, and selective reshaping of immune cell populations.
Paired BCR and TCR data were available for 542 individuals. Mal-ID correctly classified immune status from blood samples of 542 individuals with both BCR and TCR data. High classification ...
Therefore, TCR and BCR sequencing could, in theory, inform disease diagnosis, but this is extremely challenging, owing to technical limitations and the enormous complexity of the data. Zaslavsky ...
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Machine learning tool decodes immune receptor sequences to diagnose multiple diseasesIn the study, "Disease diagnostics using machine learning of B cell and T cell receptor sequences," published in Science, researchers analyzed BCR heavy chain and TCR beta chain sequences from 593 ...
Parse Biosciences, the leader in accessible and scalable single cell sequencing, today affirmed their plans to proceed with ...
Molecular Applications in BCR::ABL1-Negative Myeloid Neoplasms Certain ... Clonal T-cell receptor (TCR) gene rearrangement detection remains pivotal in distinguishing reactive and neoplastic ...
Its growing portfolio of products includes Evercode Whole Transcriptome, Evercode TCR, Evercode BCR, CRISPR Detect, Gene Select, and an interactive data analysis solution, Trailmaker. Parse ...
Its growing portfolio of products includes Evercode Whole Transcriptome, Evercode TCR, Evercode BCR, CRISPR Detect, Gene Select, and an interactive data analysis solution, Trailmaker. Parse ...
In response to pathogens, vaccines, and other antigenic stimuli, BCR and TCR repertoires undergo changes through clonal expansion, somatic mutation, and selective reshaping of immune cell populations.
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