Compromised antigen presentation ranks among the top mechanisms that render cancers non-immunogenic (non-responsive to immune ...

A team of researchers has successfully created more effective immune cells that can fight cancer without damaging healthy ...

image: QRICH1 fine-tunes the signaling of T cell receptors by regulating CARD11 view more Credit: Nicole M. Carter In a study ...

The answer turned out to be a cutting-edge treatment that few Americans know about, according to Roswell Park Comprehensive Cancer Center in Buffalo, N.Y., the hospital that treated Vogelsang. CAR ...

A team of researchers from the University of Chicago, in collaboration with researchers from the University of Pittsburgh, ...

Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team from the Technical University of Munich (TUM) and Helmholtz ...

Author for correspondence Tel.: +44 191 222 5462 steven.o'[email protected] T cells develop in the thymus, where they undergo positive and negative selection to produce a nonself-binding T ...

Physician-scientists at Memorial Sloan Kettering Cancer Center (MSK) recently published two papers that advance the science of addressing critical issues with CAR T cell therapy in patients with ...

CAR T-cell therapy has significantly improved outcomes for B-ALL patients, but relapse still occurs in over 50% of cases, leaving many with limited treatment options. Ongoing research aims to ...

Even in the case of uncomplicated infections, the body prepares itself early on for the possibility of a more severe course. A research team has now uncovered this mechanism. The scientists showed ...