Researchers at the University of Gothenburg have identified a small molecule, PZL-A, that restores function in the defective POLG enzyme, critical for mitochondrial DNA replication. The compound has ...

The other approach analyzes mitochondrial DNA, or mtDNA. Because mtDNA tends to survive long after nuclear DNA has disintegrated, this approach is useful in identifying the remains of persons who ...

When the mechanisms that replicate or repair mitochondrial DNA (mtDNA) fail, it can cause a wide range of syndromes for which there are few to zero existing treatment options. One of the causes of ...