The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

In cancer and obstructive disease, the ECM has a critical role in pathogenesis. The challenge in these settings will be to find therapies that prevent hyperproliferation and encourage proper ...

The tumor microenvironment (TME) is a complex and dynamic network consisting of tumor cells, immune cells, stromal cells, ...

Mapping a tumor's cellular neighborhood in three dimensions could identify potential targets for personalized cancer therapy.

CAFs Impact ECM and tumor growth: CAFs secrete MMPs to degrade ECM, releasing growth factors for cancer cells. ECM changes counteract CAFs and tumor cells: (a) Hard ECM triggers Twist release from ...

Adhesive Interactions Influencing Metastases Integrins are the major extracellular matrix (ECM) receptors, and integrin-mediated adhesive interactions between tumor cells and the components of ...

research published in Nature Communications* on the 14th of February details how the structure of the extracellular matrix (the ECM) acts as a physical roadmap, which actively guides cancer cells ...

ADAMTS5 functions like a pair of scissors by cleaving proteins within the extracellular matrix (ECM), the tissue surrounding tumors. This process creates pathways that enable ovarian cancer cells ...

Detailed price information for Pyxis Oncology Inc (PYXS-Q) from The Globe and Mail including charting and trades.