Lacks well-eastablished analytical tools Researchers have observed that mutations in the TERT promoter elevate cancer risk through telomere lengthening. 18 For example, promoter mutations that create ...

When the researchers transformed these cells with a mutant form of mTERT -- HH-TERT, which cannot bind ... These findings indicate that telomere length is not directly correlated with evasion ...

In stem cells, telomerase extends the telomeres so that cell division can continue, perhaps indefinitely. In somatic cells, telomerase is inactive in part because the gene encoding telomerase’s ...

W. Szostak and Carol W. Greider — was awarded the Nobel Prize in Physiology or Medicine for her help in discovering "how chromosomes are protected by telomeres." Telomeres protect our DNA ...

Telomeres are specialized nucleoprotein structures at the ends of eukaryotic chromosomes that are essential for chromosome stability and cellular proliferation. Telomeric DNA does not encode for ...

BEIJING, April 15 (Xinhua) -- Scientists have successfully completed the world's first telomere-to-telomere (T2T) genome assembly of hexaploid bread wheat, marking a major breakthrough in wheat ...