IDEC Pharmaceuticals’s initial customized approach was circumvented by the work to develop anti-CD20 antibodies. Like other researchers, they derived their monoclonal antibodies from mice. So, to ...

CD20 is a CD marker—a molecule on the cell ... mix of construction materials' to craft the antibody, some human, some mouse; some are humanized (obinutuzumab) and some are fully human ...

Rituximab, a CD20-specific monoclonal antibody that depletes ... Studies of experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis, have shown that B cells markedly ...